Abstract: To study the precipitation mechanism of α-Cr phase in Inconel 718 alloy, the samples after long-time aging at 650 and 677℃ were examined by microstructural observations and chemical phase analysis methods. Combining the thermodynamics and kinetics calculation results, α-Cr always precipitates in the vicinity of δ phase, because δ phase rejects Cr into the γ-matrix when growing. The selected area diffraction patterns confirm that the crystallographic relationships of α-Cr with δ phase are (010)_δ//(1 10)_α-Cr and 100_δ//111_α-Cr. A graphic model is also presented to show the crystallographic relation between α-Cr and δ phases.