The optimized use of MgO flux in the agglomeration of high-chromium vanadium-titanium magnetite was investigated systematically through sinter and pellet experiments. MgO was added in the form of magnesite. When the content of MgO in the sinter was increased from 1.95wt% to 2.63wt%, the low-temperature reduction degradation index increased from 80.57% to 82.71%. When the content of MgO in the pellet was increased from 1.14wt% to 2.40wt%, the reduction swelling index decreased from 15.2% to 8.6%; however, the compressive strength of the oxidized pellet decreased dramatically and it was 1985 N with an MgO content of 1.14wt%. This compressive strength does not satisfy the requirements for blast-furnace production. When all of the aforementioned results were taken into account, the sinter with a high MgO content (2.63wt%) matching the pellet with a low MgO content (less than 1.14wt%) was the rational burden structure for smelting high-chromium vanadium-titanium magnetite in blast furnaces.