Abstract: Nanotubes, such as boron nitride nanotubes (BNNTs) and carbon nanotubes (CNTs), exhibit excellent mechanical properties. In this work, high-quality BNNTs were synthesized by ball milling and annealing. Subsequently, well-dispersed 3vol% BNNTs/Cu and 3vol% CNTs/Cu composites were successfully prepared using ball milling, spark plasma sintering, and followed by hot-rolling. Moreover, the mechanical properties and strengthening mechanisms of BNNTs/Cu and CNTs/Cu composites were compared and discussed in details. At 293 K, both BNNTs/Cu and CNTs/Cu composites exhibited similar ultimate tensile strength (UTS) of ~404 MPa, which is approximately 170% higher than pure Cu. However, at 873 K, the UTS and yield strength of BNNTs/Cu are 27% and 29% higher than those of CNTs/Cu, respectively. This difference can be attributed to the stronger inter-walls shear resistance, higher thermomechanical stability of BNNTs, and stronger bonding at the BNNTs/Cu interface as compared to the CNTs/Cu interface. These findings provide valuable insights into the potential of BNNTs as an excellent reinforcement for metal matrix composites, particularly at high temperature.