Abstract: This review provides a systematic analysis of metal-supported solid oxide fuel cells (MS-SOFCs) as next-generation energy conversion devices. By integrating multi-scale simulations with experimental validation, we establish performance benchmarks for key components including thin electrolytes, MIEC cathodes, and corrosion-resistant metal substrates. The paper elucidates critical degradation mechanisms such as chromium poisoning and interfacial instability, while proposing mitigation strategies through advanced manufacturing techniques like plasma spraying and in situ sintering. We identify system-level challenges in thermal management, gas transport optimization, and scalable production, ultimately delineating research priorities for achieving sub-600°C operation and commercial deployment.