Advanced high strength steels have been widely used to improve crashworthiness and lightweight of vehicles. Hot forming of boron alloyed steels, like 22MnB5, could produce ultrahigh strength steel parts with no springback and accurate control of dimensions, which is very difficult for the popular cold stamping process. Moreover, the hot forming of recently developed medium-Mn steels could have many advantages over the hot formed 22MnB5, e.g. better mechanical properties and lower production cost. In this paper, the hot forming process in automotive industries, the hot formed steel grades, medium-Mn steel grades and their application in hot forming have been all reviewed in depth. In particular, the adaptability of both medium-Mn steels and the present popular 22MnB5 into the hot forming process has been compared thoroughly. Finally, the future researches are suggested on the hot forming of medium-Mn steels for succeeding in commercialization.